Painless administration of a vaccine by tiny microneedles on a skin patch. Interestingly, this mechanism of antigen exposure promotes a better immune response compared to the traditional bolus injections that make our arm’s go limp for an afternoon.
Imagine having an entire pharmacy’s worth of drugs implanted in your body primed for release upon demand. It’s like a medical “OnStar”. This idea of an implantable microchip for programmable multi-dose drug delivery finally shows proof of concept with the osteoporosis drug teriparatide.
Researchers from Rice University and Baylor College of Medicine have developed a method to grow blood vessels in a laboratory. The investigators used biomimetic polyethylene glycol hydrogels embedded with a growth factor called BB (PDGF-BB) to spur angiogenesis, and are now working on a way to guide the formation of vasculature for specific applications
Common techniques for identifying and measuring DNA or RNA require purification, labeling, or other cumbersome preparations. But a new method pumps samples through a tiny capillary tube and needs no such pretreatment
Fluorescent Nanoparticles Fresh From The Microwave
To make the particles, Mao, with Shukun Xu and colleagues in China, mixed acetates of the rare earth elements yttrium, ytterbium, and erbium; NH4F; and NaCl in the microwave at 160 °C for one hour. The resulting nanoparticles, he says, are comparable in quality to those made under more stringent conditions. The researchers then attached the nanoparticles to antibodies and used the resulting complexes to label cells in a petri dish. How they will fare in vivo remains to be seen, Mao says.
A small group of diverse individuals living on at least three continents have solved the structure of a protein that has stumped scientists for more than 10 years. And they did so playing an online protein folding game called Foldit.